Abstract：Objective: To investigate the changes of anterior chamber depth (ACD) after phacoemulsification cataract extraction (PE) combined with intraocular lens (IOL) implantation, and to analyze the influencing factors of anterior chamber (AC) exudation.Methods: The clinical data of 315 cataract patients (342 eyes) who underwent PE combined with IOL implantation in our hospital from January 2016 to December 2018 were selected, and the patients were divided into two groups according to whether AC exudation occurred after surgery.There were 19 patients (21 eyes) in the AC exudative group and 296 patients (321 eyes) in the AC non-exudative group.The ACD changes of cataract patients before and after 1 day, 1 week, 1 month, and 2 months were compared, and the influencing factors of AC exudation were analyzed by binary logistic regression.Results: The ACD at different time points after surgery was significantly higher than that before surgery, and the ACD at 2 months after surgery was significantly lower than that at 1 day, 1 week, and 1 month after surgery, with significant differences (P<0.05).As to intraoperative pupil diameter, history of alcohol abuse, smoking history, history of hypertension, history of heart disease, history of diabetes, history of prostatic hyperplasia, history of rheumatoid arthritis in the AC exudation group, the difference was not significant in the AC non-exudation group, which was not an influencing factor (P>0.05).High myopia, preoperative intraocular pressure (IOP), glaucoma, preoperative visual acuity, intracapsular rupture of the lens (PCR), and ultrasound cumulative energy, the composite parameters (AECP), uveitis, and lens nucleus classification were significantly different between the groups, all of which were factors influencing AC exudation (P<0.05).By binary logistic analysis, high myopia, preoperative IOP>21mmHg, glaucoma, intraoperative PCR, ultrasound AECP>7.25 (% × min), uveitis, and lens nucleus grading ≥ Ⅳ are risk factors for AC exudation ( P<0.05).Conclusion: ACD gradually increased after surgery, and it was close to normal 2 months after surgery.For patients with risk factors for postoperative AC exudation, preventive measures should be taken and treated in a timely manner.
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2020, Vol. 26 
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