Abstract：Objective: To investigate the long-term vision recovery, corneal cell changes and related influencing factors after femtosecond laser assisted cataract surgery. Methods: 73 cases of cataract patients who underwent femtosecond laser assisted cataract surgery in our hospital from August 2015 to July 2017 were selected as the research objects. The changes of visual acuity and corneal endothelial cell count were observed before operation, 1 day after operation, 1 week after operation, 1 month after operation and 6 months after operation; According to the loss of corneal endothelial cells, they were divided into severe loss group and general loss group. Firstly, the variables with statistical significance were included in logistic regression and the univariate analysis was used to analyze the risk factors of severe corneal endothelial cell loss. Results: There were significant differences in myopia, hyperopia and corneal endothelial cell count at different time points (P<0.05). The visual acuity of naked myopia and naked hyperopia at 1 week, 1 month and 6 months after operation was significantly higher than that before operation. 1 week after operation was significantly higher than 1 day after operation. 1 month after operation was significantly higher than 1 day and 1 week after operation. 6 months after operation was significantly higher than 1 day, 1 week, 1 month and 6 months after operation, the difference was statistically significant (P<0.05). Conclusion: Femtosecond laser-assisted cataract surgery can improve the visual acuity of patients, but there is corneal loss in patients. Age, preoperative lens nucleus hardness grade, preoperative anterior chamber depth and preoperative axial length are the influencing factors and independent risk factors of severe corneal loss, which should be paid special attention to in clinical.
段琼, 王飞, 王飞, 马波. 飞秒激光辅助白内障手术后患者远期视力恢复情况角膜内皮细胞变化及相关因素探讨[J]. 河北医学, 2020, 26(8): 1324-1328.
DUAN Qiong, et al. Long-term Visual Recovery, Changes of Corneal Endothelial Cells and Related Factors in Patients with Cataract Surgery Assisted by Femtosecond Laser. HeBei Med, 2020, 26(8): 1324-1328.
[1] Ahmed A Alnagdy, Hossam Y Abouelkheir, Sherief E El-Khouly, et al. Impact of topical nonsteroidal anti-inflammatory drugs in prevention of macular edema following cataract surgery in diabetic patients[J]. International Journal of Ophthalmology, 2018, 11(4):616~622. [2] 张舒琪, 张素华, 刘迁, 张哲.飞秒激光辅助白内障手术联合三焦点人工晶状体植入术的疗效观察[J].国际眼科杂志, 2019, 19(6):1044~1047. [3] Lin Shen, Peng Sun, Canwei Zhang, et al. Therapy of corneal endothelial dysfunction with corneal endothelial cell-like cells derived from skin-derived precursors[J]. Scientific Reports, 2017, 7(1):13400. [4] Teoh L S, Foo S W, Mansurali V N, et al. Evaluation of corneal endothelial cell loss after uncomplicated phacoemulsification cataract surgery with intracameral phenylephrine[J]. 2017, 6(4):1~6. [5] Kazutaka Kamiya, Kei Iijima, Shoji Nobuyuki, et al. Predictability of intraocular lens power calculation for cataract with keratoconus: a multicenter study[J]. 2018, 8(1):1312. [6] 陈润连, 刘晓军, 邓钜良.飞秒激光白内障与传统超声乳化白内障手术的效果对照研究[J].中国医药科学, 2019, 9(6):246~248. [7] 王晓明, 汤欣, 党光福, 等.飞秒激光辅助的白内障手术对硬核白内障的临床效果研究[J].中国实用眼科杂志, 2017, 35(9):890~895. [8] 范巍, 张广斌.角膜内皮营养不良患者飞秒激光辅助白内障手术观察[J].中华眼外伤职业眼病杂志, 2018, 40(1):40~44. [9] 陈炳衡, 柯妍, 汤秀娟, 等.飞秒激光辅助白内障手术后角膜内皮细胞变化及其影响因素的临床分析[J].临床眼科杂志, 2018, 26(4):335~339. [10] Jain K , Malik K P S , Gupta S . Corneal status following modified Blumenthal technique of manual small incision cataract surgery (MSICS) compared to phacoemulsification in treatment of grade III or more nuclear sclerosis-cohort study[J]. Nepalese Journal of Ophthalmology, 2015, 7(1):47~51. [11] Assil K , Harris L , Cecka J . Transverse vs torsional ultrasound: prospective randomized contralaterally controlled study comparing two phacoemulsification-system handpieces[J]. Clinical Ophthalmology, 2015, 9(1):1405~1411.
2020, Vol. 26 
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