Abstract：Objective:To investigate the effects of combination therapy of crotonone and Xingnaojing in the treatment of acute alcoholism with arrhythmia. Methods: A total of 130 patients with acute alcoholism and acute alcoholism with arrhythmia were enrolled in our hospital from January 2016 to December 2018. They were divided into control group and treatment group. For the control group, naloxone was administered mainly on the basis of conventional treatment, and for the treatment group, naloxone combined with Xingnaojing was used for the combined treatment. The clinical treatment effects of the two groups of patients were compared to analyze the effects of drug onset and symptom improvement and consciousness recovery, and to compare the occurrence of adverse conditions. Results: In the treatment group, 28 patients were cured and 32 were improved. The effective rate was 92.31% in the treatment group, better than that of the control group, which was 70.77% (P<0.05).The duration of central arrhythmia in the treatment group was (58.88±14.13) min (P<0.05), and in the control group it was comparatively significantly longer (P<0.05). The onset time of the treatment group was (38.74±5.25) min, which was significantly shorter than that of the control group (P<0.05), and the symptom improvement time of the treatment group was also lower than that of the control group (P<0.05). The disappearance time of excitatory and ataxia symptoms in the treatment group was (80.23±10.25) min. The treatment group was superior to the control group in the time of excitement and ataxia disappearance and the conscious time (P<0.05). In the treatment group, there were 6 cases of palpitations, 1 case of hypotension, 3 cases of nausea and vomiting, which were different from the control group, and the incidence of adverse reactions was significantly lower (P<0.05). Conclusion: In the treatment of patients with acute alcoholism complicated with arrhythmia, naloxone combined with Xingnaojing treatment has significant clinical effects, which can significantly improve a series of side effects caused by alcoholism and reduce the occurrence of adverse symptoms.
2020, Vol. 26 
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