Effects of Different Hemostatic Methods Used in Laparoscopic Cystectomy for Ovarian Endometriosis Cyst on Ovarian Reserve Function, Menstruation and Sex Hormone Levels
LUO Aimin, DU Zhen, CHEN Zhimei, et al
The Second People's Hospital of Hainan Province, Hainan Wuzhishan 572299, China
Abstract：Objective: To investigate the effects of different hemostatic methods used in laparoscopic cystectomy for ovarian endometriosis cyst (OEC) on ovarian reserve function, menstruation and sex hormone levels. Methods: 106 patients with OEC who were admitted to the hospital from January 2016 to January 2019 were selected as the subjects. They were divided into the control group (bipolar coagulation hemostasis, n=53) and the observation group (suture hemostasis under laparoscope, n=53) according to the operation method. The ovarian reserve function [antral follicle count (AFC), ovarian artery peak systolic velocity (PSV) at affected side ovarian artery], sex hormones [follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2)], menstrual recovery and follow-up pregnancy outcomes were compared between the two groups. Results: There were no significant differences in AFC, PSV, FSH, LH, E2, menstrual time or menstrual cycle between the two groups before operation (P>0.05). There was no significant difference in AFC or PSV in the observation group at 3rd and 6th month months after operation, compared with those before operation (P>0.05). AFC and PSV in the control group were significantly lower than those before operation (P<0.05). Besides, AFC and PSV in the observation group were significantly higher than those in the control group (P<0.05). The difference of menstrual duration and menstrual cycle of the observation group before and after treatment was bigger than that of the control group (P<0.05). There was no significant difference in the level of FSH, LH or E2 in the observation group at 6th month after operation, compared with those before operation (P>0.05). The levels of FSH and LH in the control group were significantly increased and E2 levels were significantly decreased (P<0.05). The difference of L2, LH and E2 in the observation group before and after treatment was smaller than that in the control group (P<0.05). The natural pregnancy rate of the observation group was 33.96% at 1 year after operation, significantly higher than that of the control group (15.09%) (P<0.05). Conclusion: Compared with bipolar coagulation hemostasis, suture hemostasis causes less damage to the ovarian reserve function in patients having undergone laparoscopic cystectomy for OEC. It is more conducive to menstrual recovery and stable sex hormone levels, and the clinical positive effect is more obvious
骆爱民, 杜珍, 陈志美, 梁月珍. 腹腔镜下卵巢子宫内膜异位囊肿剥除术中应用不同止血方式对患者卵巢储备功能月经及性激素水平的影响[J]. 河北医学, 2020, 26(5): 747-751.
LUO Aimin, DU Zhen, CHEN Zhimei, et al. Effects of Different Hemostatic Methods Used in Laparoscopic Cystectomy for Ovarian Endometriosis Cyst on Ovarian Reserve Function, Menstruation and Sex Hormone Levels. HeBei Med, 2020, 26(5): 747-751.
2020, Vol. 26 
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