Abstract：Objective: To explore the differences of anesthetic effects of remifentanil, etomidate or lidocaine combined with propofol for painless induced abortion in outpatients. Methods: 108 cases of patients with painless induced abortion admitted to our hospital from January 2017 to March 2018 were divided into three groups according to thecomputer random number method, including group I (remifentanil combined with propofol anesthesia, n=36), group Ⅱ (etomidate combined with propofolanesthesia, n=36) and group Ⅲ (lidocaine combined with propofol, n=36). The intraoperative hemodynamic changes, analgesic effects, anesthetic effects, postoperative recovery and adverse reactions were detected and compared. Results: There were significant differences in the betweee-groups effects, time effects and interaction effects of MAP and HR (P<0.05), but there were no significant differences in the betweee-groups effects, time effects and interaction effects of SpO2 (P>0.05). , The MAP and HR in groups I and Ⅲ at T1 and T2 were lower than those at T0 (P<0.05), and the MAP and HR in group Ⅱ at T1 and T2 were higher than those in group I, and the MAP and HR in group Ⅲ at T1 and T2 were lower than those in group Ⅱ (P<0.05). There were no significant differences among the three groups in Ramsay score and anesthetic effects (P>0.05), and the VAS score in group Ⅱ was significantly lower than that in the other two groups (P<0.05), and there was no significant difference in VAS score between group I and group Ⅲ (P>0.05). The blinking time, spontaneous breathing and recovery walking time in group Ⅱ were significantly longer than those in the other two groups (P<0.05), and there was no significant difference between group I and group Ⅲ (P> 0.05). Adverse reactions of injection pain, nausea, lethargy, dizziness and postoperative pain were observed in all three groups, but the difference was not statistically significant (P>0.05). Conclusion: All the three groups have good anesthetic effects. Compared with the other two groups, etomidate combined with propofol anesthesia has better anesthetic effects, smaller blood flow fluctuation during operation and lighter postoperative pain degree, but slightly longer postoperative consciousness recovery time.
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2019, Vol. 25 
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