Abstract：Objective: To explore the value of real-time ultrasonic shear wave elastic imaging in evaluating the biological properties of quadriceps muscle in patients with knee arthritis by observing the changes of the elastic modulus of shear wave under the ultrasound of those patients’ quadriceps muscle. Methods: 40 female patients diagnosed with knee osteoarthritis (observation group) and 40 healthy female volunteers (control group) were examined by ultrasonic shear wave elastic imaging. The lower extremity muscle chain training treatment was given to the patients belong to the observation group, and ultrasonic shear wave elastic imaging was examined before and 3 months after treatment. The difference of elastic modulus of femoral rectus muscle, medial femoral muscle and lateral femoral muscle before and after treatment was compared between the observation group and the control group. After that, the hardness changes of lower extremity muscle in female knee osteoarthritis patients were quantitatively analyzed. Results: In observation group before treatment the mean elastic modules of femoral rectus muscle (7.03±1.07) kpa, medial femoral muscle (6.87±1.64) kpa, lateral femoral muscle (7.00±1.23) kpa, were lower than that rectus muscle (9.07±1.52) kpa, medial femoral muscle (7.96± 0.94) kpa, lateral femoral muscle (8.33±1.10) kpa in the control group, the difference is statistically significant (P＜0.01).After treatment the mean elastic modules of femoral rectus muscle (8.17±1.00) kpa, medial femoral muscle (7.35±1.11) kpa, lateral femoral muscle (7.80±0.89) kpa in the observation group were higher than that before treatment, and the comparison was statistically significant (P＜0.01 or P＜0.05). Conclusion: The real-time ultrasonic shear wave elastic imaging technique could be used to quantitatively evaluate the biomechanical properties of knee arthritis patients, which supplements the new observation basis for the diagnosis and efficacy evaluation of knee osteoarthritis. It has high clinical application value and research prospect.
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2019, Vol. 25 
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