Abstract：Objective: To study the continuous renal replacement therapy (CRRT) in patients with kidney syndrome (CRS) 1 core and analyzes the factors affecting prognosis. Methods: 66 patients with type 1 cardiorenal syndrome admitted to our hospital from July 2017 to September 2018 were retrospectively collected. According to the death during hospitalization, 31 cases were divided into survival group and 35 cases into death group. The clinical indicators, laboratory examination indicators, treatment parameters and left ventricular ejection fraction levels of the two groups were compared, and multivariate logistic regression analysis was made. Results: The interval between diagnosis and treatment in survival group was (3.2 +0.8) days, which was lower than that in death group (5.1 +1.2) days, with significant difference (P<0.05). The levels of alanine aminotransferase, total bilirubin and serum creatinine in survival group were lower than those in death group, and there were significant differences (all P<0.05). The left ventricular ejection fraction of survival group was (60.4 +10.3)%, which was higher than that of control group (50.7 +9.2)%. The difference was significant (P<0.05). Multivariate logistic regression analysis showed that the interval between diagnosis and treatment was a risk factor for death in CRRT patients with type 1 cardiorenal syndrome, while left ventricular ejection fraction was a protective factor. Conclusion: CRRT has a poor prognosis for type 1 CRS patients. The interval between diagnosis and treatment is an independent risk factor for death, while left ventricular ejection fraction is a protective factor.
2019, Vol. 25 
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