Abstract：Objective: To explore the correlation between Th1/Th2 immune imbalance and different types of Henoch-Schonlein purpura. Methods: A total of 90 patients with Henoch-Schonlein purpura who were treated in department of dermatology of the Affliated hospital of Chengde Medical College between December 2016 and December 2017 were collected. Thirty patients with allergic purpura who have renal injury and Thirty patients who have gastrointestinal injury were selected as the research object,which were named as purpura nephritis group and purpura abdominal type group. While 30 cases of simple purpura patients were used as the control group in the same period. IL-2, IL-4 were detected and the datas were compared. Results: The level of IL-2 in the purpura nephritis group and the purpura abdominal type group, was significantly lower than control group (P<0.05), the level of IL-4 was significantly higher than control group (P<0.05).The purpura nephritis group compared with the purpura abdominal type group,the difference both was not statistically significant(P＞0.05). Conclusion: The different types of Henoch Schonlein purpura is correlated with the imbalance of Th1/Th2, which can provide new evidence for the clinical treatment and prognosis of Henoch Schonlein purpura.
齐海花, 何磊, 黄占强, 丁华杰, 段昕所. 不同分型过敏性紫癜患者外周血Th1/Th2型细胞因子的相关性研究[J]. 河北医学, 2019, 25(6): 996-997.
QI Haihua, HE Lei, HUANG Zhanqiang, et al. Study on the Correlation between Th1/Th2 Cytokines in Peripheral Blood of Patients with Different Types of Henoch Schonlein Purpura. HeBei Med, 2019, 25(6): 996-997.
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2019, Vol. 25 
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