欣普贝生与小剂量缩宫素对足月妊娠羊水偏少引产的疗效观察

doi:10.3969/j.issn.1006-6233.2019.03.039

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摘要目的:探究欣普贝生与小剂量缩宫素对足月妊娠羊水偏少引产的治疗效果。方法:回顾性分析我院欣普贝生引产(观察组)及小剂量缩宫素引产(对照组)羊水偏少的足月妊娠孕妇各48例临床资料。比较两组给药前及给药12h后宫颈成熟情况(Bishop评分),并记录两组临产所需时间、引产情况、妊娠结局及并发症发生情况差异。结果:给药12h后,两组Bishop评分均较给药前升高(P<0.05),且观察组高于对照组(P<0.05)。观察组临产所需时间、孕母不良结局总发生率、胎儿不良结局总发生率及并发症总发生率明显低于对照组(P<0.05),引产成功率及引产总有效率则明显高于对照组(P<0.05)。结论:欣普贝生与小剂量缩宫素对足月妊娠羊水偏少孕妇引产均有利,但欣普贝生能促进宫颈成熟,为引产提供更适宜子宫内环境,而提高引产成功率,并降低并发症发生率,于改善母婴结局有积极意义。

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	姚静

关键词 ：羊水偏少, 足月妊娠, 引产, 欣普贝生, 缩宫素

Abstract：Objective: To explore the therapeutic effect of Himpelson and low dose oxytocin on induced labor with oligohydramnios in full-term pregnancy. Methods: The clinical data of 48 cases of full-term pregnant women with oligohydramnios treated with Dinoprostone for labor induction (observation group) and low-dose oxytocin for labor induction (control group) were retrospectively analyzed. The cervical ripening (Bishop score) was compared between the two groups before administration and after 12h of administration, and the time required for labor, labor induction, pregnancy outcomes and occurrence of complications were recorded in the two groups. Results: After 12h of administration, the Bishop score in the two groups was higher than that before administration (P<0.05), and the score in observation group was higher than that in control group (P<0.05). The time required for labor, and the total incidence rates of maternal adverse outcomes, fetal adverse outcomes and complications in observation group were significantly lower than those in control group (P<0.05), and the success rate of induction and the total effective rate of labor induction were significantly higher than those in control group (P<0.05). Conclusions: Dinoprostone and low-dose oxytocin are beneficial for labor induction in pregnant women with oligohydramnios in full-term pregnancy. However, Dinoprostone can promote cervical ripening and provide a more suitable intrauterine environment for labor induction, and increase the success rate of labor induction, and reduce the incidence rate of complications, and it has a positive effect on improving the maternal-infant outcomes.

Key words： Oligohydramnios Full-term pregnancy Labor induction Sinoprostone Oxytocin

基金资助:湖北省卫生厅科研项目,(编号:1309254)

引用本文:

姚静. 欣普贝生与小剂量缩宫素对足月妊娠羊水偏少引产的疗效观察[J]. 河北医学, 2019, 25(3): 679-682.
YAO Jing. Observation of Effect of Himpelson and Low Dose Oxytocin on Induced Labor with Oligohydramnios in Full-term Pregnancy. HeBei Med, 2019, 25(3): 679-682.

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http://www.hbyxzzs.cn/CN/10.3969/j.issn.1006-6233.2019.03.039 或 http://www.hbyxzzs.cn/CN/Y2019/V25/I3/679