Abstract：Objective: To study the efficacy of rat neurotrophic factor in the treatment of cerebral infarction and its effects on plasma D-D, TXB2 and BNP. Methods: From April 2015 to March 2016, 120 patients with cerebral infarction were selected in our hospital, those patients were randomly divided into control group (60 cases) and experimental group (60 cases) according to simple random grouping. The control group was treated with conventional drugs. The experimental group were given nerve growth factor to complete the treatment on the basis of control group. The clinical efficacy, daily living ability (ADL) and neurological score, plasma D-D, TXB2 and BNP levels were compared between the two groups. Results: After treatment, the total effective rate was 83.33% in the experimental group was significantly higher than that in the control group 70.00% (P<0.05). The scores of ADL in the experimental group were significantly higher than those in the control group [(64.60±5.13)points VS(54.51±5.33)points] (P<0.05), NIHSS score was significantly lower than that of the control group [(9.49±1.03)points VS (15.04±1.17) points] (P<0.05). The levels of DD, TXB2 and BNP in the test group were significantly lower than those in the control group [(0.47±0.04)mg/L,(46.14±3.88)ng/L,(10.93±1.29)pg/ml VS(1.23±0.15)mg/L, (68.80±6.19)ng/L,(18.56±2.07)pg/ml](P<0.05). Conclusion: The treatment of neurological growth factor in patients with cerebral infarction can effectively reduce the levels of plasma D-D, TXB2 and BNP, improve the clinical symptoms of patients, the clinical efficacy is good and the safety is high.
尹行志. 鼠神经生长因子治疗脑梗死的临床疗效评价及对血浆D-D TXB2 BNP的影响[J]. 河北医学, 2019, 25(2): 215-218.
YIN Xingzhi. Clinical Effect of Neuropathic factor in the treatment of Cerebral Infarction and its effect on plasma D-D, TXB2 and BNP. HeBei Med, 2019, 25(2): 215-218.
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2019, Vol. 25 
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