Abstract：Objective:To investigate the value of tuberculosis interferon γ (IFN-γ) release assay combined with hydrothorax and ascites adenosine deaminase (ADA) detection in the diagnosis of tuberculosis. Methods: A total of 150 patients with suspected tuberculosis treated in our hospital during the period from December 2016 to February 2017 and 30 healthy volunteers (healthy group) who received physical examination in our hospital during the same period were enrolled in this study. They were divided into the tuberculosis group and the non-tuberculosis group according to the results of percutaneous biopsy. All patients underwent tuberculosis IFN-γ release assay, and samples of hydrothorax and ascites was collected for ADA detection. Results: The positive rate of IFN-gamma release assay, ADA level in pleural and ascites, IFN-gamma release assay and ADA positive rate in pleural and ascites in tuberculosis group were significantly higher than those in non-tuberculosis group and healthy group (P<0.05), but there was no significant difference between non-tuberculosis group and healthy group (P > 0.05). IFN-gamma release assay combined with ADA in pleural and ascites was more effective in the diagnosis of tuberculosis than the single test. Conclusion: The combination of tuberculosis IFN-gamma release assay and detection of ADA level in pleural and ascites can effectively improve the clinical diagnosis of tuberculosis. It is suitable for clinical popularization and application.
白云,王海峰,朱红艳. 结核γ-干扰素释放分析试验联合胸腹水ADA检测在结核病诊断中的应用研究[J]. 河北医学, 2018, 24(11): 1910-1913.
BAI Yun, WANG Haifeng, ZHU Hongyan. Application of Tuberculosis Interferon γ-release Assay combined with Hydrothorax and Ascites ADA Detection in the Diagnosis of Tuberculosis. HeBei Med, 2018, 24(11): 1910-1913.
2018, Vol. 24 
冀公网安备13080202000677号