Abstract：Objective: To analyze the clinical features of heart failure with multiple etiological factors in seniors, so as to provide scientific basis for clinical prevention and treatment. Methods: A retrospective analysis was made on hospitalized medical records of heart failure patients aged 60 or above in our hospital. According to the number of etiological factors divided into single-cause group, double-cause group and multi-cause group were compared to summarize the clinical characteristics of multi-cause heart failure. Results: A total of 249 cases of senile heart failure were collected, of which there were 83 cases of single pathogeny group, 79 cases of two pathogenesis group and 87 cases of multiple pathogenesis group. The most common combination of double pathogenesis was coronary heart disease and hypertension (28 cases, 35.4%). There were 46 cases (52.9%) with three etiological factors and 34 cases (39.1%) with four etiological factors in the multi-etiological group. The indexes of age, NYHA class III-IV, brain natriuretic peptide (BNP) elevation, hospitalization time and the number of drugs taken in the two groups were significantly higher than those in the single-cause group, while those in the multi-cause group were significantly higher than those in the double-cause group (age F=53.05, P<0.01; cardiac function class χ2=15.83, P<0.01; brain natriuretic peptide χ2= 18.58, P<0.01). Hospitalization time F=28.61, P<0.01; medication type F = 18.81, P<0.01; hospitalization mortality increased with the increase of etiology, but no statistical difference was found (χ2=1.823, P=0.twin). Conclusion: The heart failure with multiple etiological factors in seniors are many with advanced age with comorbid diseases. The state of an illness and its treatment were complication as well as the hospital stays were prolonged with a poor prognosis.
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2018, Vol. 24 
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