Curative Efficacy of Insulin Sensitizer in Treatment of Type 2 Diabetes Intensive Treatment after Long-term Remission and its Effects on Urine Microalbumin
CHEN Hongxia, et al
Beijing First Hospital of Integrated Chinese and Western Medicine, Beijing 100026,China
Abstract：Objective: To study curative efficacy of insulin sensitizer in treatment of type 2 diabetes intensive treatment after long - term remission and its effects on urine microalbumin. Methods: 80 patients of type 2 diabetes mellitus who received therapy from April 2015 to April 2016 were selected as research objects. According to random number table method,those patients were divided into the observation group(n=40) and the control group(n=40). The control group was treated with secondary double-arc treatment,while the observation group was treated with Insulin sensitizer treatment.Then blood sugar,insulin,C peptide,HDL-C, LDL-C, Homa-IR and UAE level were compared. Results: After treatment,the level of FBG and PBG in observation group was less than the control group after 1 month and 2 months(P<0.05). There was no significant difference in HbA1c levels between the two groups after 1 and 2 months of treatment(P>0.05). Two groups of FINS levels in the treatment of 1, 2 months after the decline. There were no significant differences in FINS, PINS, FC-P and PC-P between the two groups after 1 and 2 months (P> 0.05). HDL-C indicator in Observation group was higher than the control group[(1.51±0.55) mmol/L vs(1.27±0.46)mmol/L](P<0.05). LDL-C indicator in Observation group was less than the control group[(2.92±0.71) mmol/L vs(3.36±0.79)mmol/L](P<0.05). UAE level in Observation group was less than the control group [(98.27±56.23) C/mg.(24h)-1vs(143.22±51.37) C/mg。(24h)-1](P<0.05). Conclusion: Insulin sensitizer treatment of type 2 diabetes can effectively reduce the level of blood glucose and FINS, so that the sensitivity of peripheral tissue in the insulin to improve and reduce the level of urinary albumin in patients with significant efficacy, worthy of promotion.
陈红霞, 帅瑛, 袁群, 邢小燕, 马丽荣, 李瑞杰. 胰岛素增敏剂在2型糖尿病强化治疗后长期缓解中的作用及对尿微量白蛋白的影响[J]. 河北医学, 2018, 24(7): 1100-1103.
CHEN Hongxia, et al. Curative Efficacy of Insulin Sensitizer in Treatment of Type 2 Diabetes Intensive Treatment after Long-term Remission and its Effects on Urine Microalbumin. HeBei Med, 2018, 24(7): 1100-1103.
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2018, Vol. 24 
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