Abstract：Objective: To explore the clinical significance of detecting serum inflammatory factors and biochemical indexes in patients with vascular dementia (VD) so as to provide reference for the clinical diagnosis of patients with this disease. Methods: 82 patients with vascular dementia (observation group) admitted to our hospital from October 2012 to October 2016 and 85 normal persons (control group) who underwent health examination in our hospital during the same period were enrolled in this study. Serum levels of inflammatory cytokines and life indicators, analysis of the two groups were included in the indicators of the differences between the levels. Results: The levels of IL-1β, TNF-α and IL-6 in the observation group were [(62.69 ± 31.08) pg / mL], [(8.41 ± 2.06) foml / mL] and [(10.97 ± 5.12) pg / mL] were significantly higher in the control group than those in the control group (P <0.05) The levels of Hcy, HDL-C, LDL-C, triglyceride and apolipoprotein A were [(37.51 ± 19.34) umoL / L, 0.90 ± 0.23 nmoL / L, 3.14 ± 1.11 nmoL / L, 1.74 ± 1.02 mmoL / L, / L], there was significant difference between each index level and the control group (P <0.05). There was no significant difference in the levels of other inflammatory factors and biochemical indexes between the two groups (P> 0.05). Conclusion: There are differences in inflammatory factors and biochemical indicators between vascular dementia patients and normal persons. Joint detection of inflammatory factors and biochemical indicators is helpful for clinical diagnosis of vascular dementia patients.
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2018, Vol. 24 
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