彩色多普勒超声在孕11~13<sup>+6</sup>周中胎儿颅后窝结构的检测价值

doi:10.3969/j.issn.1006-6233.2017.05.013

摘要
图/表
参考文献
相关文章 (5)

全文: PDF (1677 KB) HTML (1 KB)
输出: BibTeX | EndNote (RIS)

摘要 目的: 探究彩色多普勒超声对怀孕11~13⁺⁶周中胎儿颅后窝结构的检测价值。方法: 本次观察选取了我院在2014年2月至2016年2月在孕11~13⁺⁶周,单胎妊娠并接受颈部透明层(Nuchal Translucency, NT)检查的孕妇;其中,正常组胎儿502例,Dandy-Walker 综合征胎儿3例,统计并分析两组孕妇的基本信息数据(年龄、孕周、身高、体重、是否近亲结婚、生育史等),通过多普勒超声图像测量胎儿头臀长(Crown-Rump Length, CRL)、NT值;从胎儿颅脑的两个切面(正中矢状切面及经前卤小脑横切面)观察并测量胎儿颅后窝结构(脑干(Brain Stem, BS)直径、小脑延髓池(Cistern Magna, CM)直径、脑干至枕骨(Brain Stem to Occipital Bone, BSOB)距离)。结果: 两组孕妇在年龄、孕期、身高等基本信息上均无显著差异(P>0.05),但Dandy-Walker 综合征胎儿的CRL较正常组胎儿的短(P<0.05),而NT则较正常组胎儿的厚(P<0.05);从两个切面得到的测量值来看,与正常组胎儿比较,3例Dandy-Walker 综合征胎儿的BS及CM均减小(P<0.05),但BSOB有所增加(P<0.05)。结论: 利用彩色多普勒超声,从正中矢状切面及经前卤小脑横切面检查11~13⁺⁶周孕期的胎儿颅后窝结构,发现Dandy-Walker 综合征胎儿颅后窝结构较正常组胎儿的有所区别,BS、CM及BSOB均发生变化,即彩色多普勒超声对11~13⁺⁶周孕期胎儿的颅后窝结构检测具有一定利用价值。

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章

关键词 ：彩色多普勒超声, 颅后窝, 胎儿

Abstract：Objective: To study the value of color doppler ultrasound in testing the structure of fetus posterior cranial-fossa during 11-13⁺⁶ weeks pregnancy. Methods: The women of 11-13⁺⁶ -weeks pregnant diagnosed monocyesis and accepted nuchal translucency (NT) examination were observed in this article in our hospital from February 2014 to February 2016. There were 502 fetuses in the normal group, 3 Dandy-Walker syndrome cases were belonged to the control group. The basic information of two groups, including the women's age, gestational age, height, weight, incest, childbearing history were recorded and analyzed. Using color doppler ultrasound to measure the fetal crown-rump length (CRL) and NT value. From scanning images of posterior cranial-fossa, including median sagittal section and premenstrual halid-e cerebellum transverse section, brain stem (BS) diameter, cistern magna (CM) diameter and the distance from brain stem to occipital bone (BSOB) were measured. Results: On the basic information, such as gestational age, height, weight and so on, there have no sig-nificant difference between the normal group and Dandy-Walker syndrome cases (P>0.05), but the CRL of Dandy-Walker syndrome fetus was shorter than the normal (P<0.05), while NT value was higher than the normal (P<0.05). Moreover, in the control group, the BS and CM were decreased, however BSOB was increased (P<0.05). Conclusion: It's different about the posteri-or cranial-fossa between Dandy-Walker syndrome fetus and the normal, including BS, CM and BSOB. It proves that color doppler ultrasoundcan be used to test the structure of fetus posterior cranial-fossa during 11-13⁺⁶ weeks' pregnancy, and screen abnormal fetus.

Key words： Color doppler ultrasound Posterior cranial-fossa Fetus

基金资助:陕西省卫生厅科研基金项目,(编号:2013JM30183)

通讯作者: 闫瑞

引用本文:

张波芸, 闫瑞, 刘新, 汪越君, 陈玥锦, 李京. 彩色多普勒超声在孕11~13⁺⁶周中胎儿颅后窝结构的检测价值[J]. 河北医学, 2017, 23(5): 748-751.
ZHANG Boyun, YAN Rui, LIU Xin, et al. The Value of Color Doppler Ultrasonography in the Detection of Fetal Posterior Fossa Structure in 11-13+6 Gestation Weeks. 河北医学, 2017, 23(5): 748-751.

链接本文:

http://www.hbyxzzs.cn/CN/10.3969/j.issn.1006-6233.2017.05.013 或 http://www.hbyxzzs.cn/CN/Y2017/V23/I5/748

[1] 厉进,范雪梅,雷慧,胡伟.11~13⁺⁶周胎儿超声筛查在产前诊断中的临床价值[J].湖北医药学院学报,2016,35(4):391~393.
[2] Lafouge A,Gorincour G,Desbriere R,et al.Prenatal diagnosis of Blake’s pouch cyst following first-trimester observation of enlarged intracranial translucency[J].Ultrasound Obstet Gynecol,2012,40(4):479~480.
[3] Lachmann R,Sinkovskaya E,Abuhamad A.Posterior brain in fetuses with Dandy-Walker malformation with complete agenesis of the cerebellar vermis at 11-13 weeks:a pilot study[J].Preg Diagn,2012,32(8):765~769.
[4] 李顺振,胡兴荣,李强,等.11~13⁺⁶周正常胎儿颅后窝结构的超声评价[J].中国临床医学影像杂志,2015,26(4):271~274.
[5] 李胜利.胎儿畸形产前超声诊断学[M].人民军医出版社,2012.154~156.
[6] 徐英,孟卓,钟文明,等.超声检测孕11-13⁺⁶周胎儿颅后窝结构的临床研究[J].临床超声医学杂志,2015,17(12):805~808.
[7] Luchi C,Schifano M,Sacchini C,et al.Detailed fetal anatomy assessment in the first trimester at 11,12 and 13 weeks of gestation[J].Matern Fetal Neonatal Med,2012,25(6):675~678.
[8] Snijders RJ,Noble P,Sebire N,et al.UK multicenter project on assessment of risk of trisomy 21 by maternal age and fetal nuchal translucency thickness at 10~14 weeks of gestation[J].Fetal Medicine Foundation First Trimester Group.Lancet,1998,352(9125):343~346.
[9] 顾莉莉,李胜利,文华轩,欧阳淑媛.经前囟侧脑室横切面尾侧偏斜法在11~13⁺⁶周胎儿颜面部筛查中的应用[J].中华医学超声杂志,2015,12(12):943~950.
[10] 李红.彩色多普勒超声检查确诊胎儿畸形价值讨论[J].中国卫生产业,2013:101.
[11] 吴国旺,郝建宗,谢艳冰,等.彩色多普勒超声在产前筛查胎儿畸形中的应用价值[J].实用临床医药杂志,2013,17(15):149~150.
[12] 李昕.彩色多普勒超声在胎儿产前筛查中的应用[J].吉林医学,201,34(2):307.
[13] Shim JY,Joo DH,Won HS,et al.Hugging sister:thoracoomphalopagus with anencephaly confirmed by three-dimensional ultrasonography at 9 weeks of gestation[J].Clin Ultrasound,2011,39(5):279~282.
[14] 李胜利,张葵,田晓先.早孕期胎儿严重畸形的产前超声诊断[J].中华医学超声杂志,2016,13(2):83~95.
[15] Nicolaides KH.Turning the pyramid of prenatal care[J].Fetal Diagn Ther,2011,29(3):183~196.
[16] Salman Guraya S.The associations of nuchal translucency and fetal abnormalities,significance and implications[J].Clin Diagn Res,2013,7(5):936~941.
[17] Taipale P,Hiilesmaa V,Salonen R,et al.Increased nuchal translacency as a marker for fetal chromosomal defects[J].N Engl Med,1997,337:1654~1658.
[18] 钟静,尹家保,吕瑾玉,等.孕中晚期胎儿足长评估孕周及骨骼系统发育[J].湖北医药学院学报,2013,32(2):136~138.
[19] 陈叙,常颖,崔洪艳,等.孕11-13周⁺⁶胎儿多个超声指标联合母血清学指标在筛查染色体异常胎儿中的价值[J].中华妇产科杂志,2013,48(11):815~818.
[20] Lee MY,Won HS,Hyun MK,et al.One case of increased intracranial translucency during the first trimester associated with the Dandy-Walker variant[J].Preg Diagn,2012,32(6):602~603.