Abstract：Objective: In order to analyze the clinical applications of DSCT technique in the diagnosis of gout, the adoption of "dual source CT (dual source computed tomography, DSCT) dual energy imaging technology to detect the urate crystal deposition condition of patients with gout joints. Methods: Choosing 48 patients with clinical diagnosis of gout as the experimental group, 30 patients with other arthritis as control group (11 patients with rheumatoid arthritis, 16 patients with osteoarthritis and 3 cases of systemic lupus with lupus arthritis), it used DSCT to scan double hand-wrist joints, double knee joints and double ankle joints of patients from both groups. Using the instrumental configuration of gout recognition software to process the original images, analyzed by two experienced clinical image physicians on the data obtained, it was decided whether there's any urate crystal deposition within the checked parts of patients. Results: In the DSCT examination of 48 patients with gout, 46 cases were found in the joints with urate crystal deposition and the gout diagnostic sensitivity was 46/48 (95.8%). As for the 30 patients of the control group, there're 2 cases with pseudo signal and the specificity was 28/30 (93.3%). There's no obvious difference (P≥0.05) of the positive rate of urate crystals between gout patients who have bone destruction and those who do not have. It's found that the difference of detection rate of DSCT urate crystals has no statistical significance (P>0.05) between gout patients who have increased blood uric acid levels and normal cases. Conclusion: It has high sensitivity and specificity when using DSCT double energy imaging in the diagnosis of gout, and the urate crystals deposition condition of patients’ checked parts could be displayed intuitively with this noninvasive test. It prompts that DSCT can be applied to gout disease monitoring and has the important clinical application value.
2017, Vol. 23 
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